Molybdenum (Mo) are among the essential micronutrients and Silicon (Si) the useful element for wheat growth. In order to investigate the effect of Molybdenum and Silicon on the wheat yield (Triticumaestivum) this field experiment was conducted on Shiraz wheat cultivar at the farms of Karaj Soil and Water Research Station in 2012-12 cropping year. This experiment was carried out in as factorial in a randomized complete blocks design including two factors of Molybdenum as aluminum molybdate at three levels of zero, 10 and 20 kilogram per hectare and Silicon as sodium silicate at three levels of zero, 300 and 600 kilogram per hectare and with three replications at a sandy soil. Fertilizer recommendation was conducted according to the soil test and Water and Soil Research Institution recommendation. In order to investigate the spike length and grain number per spike, 10 samples were taken from each plot randomly before harvesting and after that wheat plants were picked from the surface of six square meters. The traits of grain yield, straw, one thousand- grain weight and the grain protein percentage were measured. The results of analysis of variance of data indicated that the treatments in which ammonium molybdate at the rate of 10 kilogram per hectare added into soil, significant and positive effect at the level of one percentage was been showed on the grain number per spike, grain yield and protein percentage. As wheat grain yield increased on average from 3566 kilogram per hectare to 4085 kilogram per hectare (14/53 percent) and the amount of protein increased from 12/89 percentage to 14/42 percent (12 percent). Molybdenum concentration of grain increased from 3/54 to 5/4 milligram per kilogram. The effect of Molybdbenum on spike length, one thousand-grain weight and straw yield was not significant. The treatment of 300 kilogram per hectare sodium silicate had significant effect on the straw yield at the level of one percentage and increased its amount from 8074 kilogram per hectare to 9188 kilogram per hectare(14 percent).